Process for preparing cepham compounds

Details Process for preparing cepham compounds Process for preparing cepham compounds

1977-02-14

1978-06-06

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424246, C07D50102

Patent

active

040938000

ABSTRACT:
A novel 4-(2'-benzothiazolyldithio)-3-imidoazetidin-2-one of the formula ##STR1## in which X is chloro or bromo and R.sub.2 is methylene or oxygen is ring-closed to the corresponding 3-exomethylenecepham or 3-"oxo" cepham by treatment with sodium or potassium iodide at a temperature of from about 40.degree. C. to about 80.degree. C.

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patent: 4008230 (1977-02-01), Koppel
patent: 4013650 (1977-03-01), Fechtig
patent: 4024152 (1977-05-01), Kukolja
patent: 4036835 (1977-07-01), Foglio et al.
patent: 4052387 (1977-10-01), Kukolja
patent: 4052408 (1977-10-01), Heusler et al.
patent: 4058521 (1977-11-01), Uyeo et al.

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