Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-06-02
1997-07-15
Davenport, Avis M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 9, 514 15, 530317, A61K 3800, A61K 3802, C07K 500, C07K 700
Patent
active
056483309
ABSTRACT:
The invention provides RGD containing peptides which are cyclized and contain hydrophobic moieties adjacent the carboxy terminus of the RGD sequence. Such peptides have an high affinity for the receptor IIb/IIIa and low affinity for the fibronectin and vitronectin receptors. Such peptides can be administered in a suitable physiologically acceptable carrier to therapeutically treat thrombosis.
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Cheng Soan
Craig William S.
Lukeman David S.
Pierschbacher Michael D.
Davenport Avis M.
La Jolla Cancer Research Foundation
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