Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1972-02-09
1976-12-28
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A61K 31505
Patent
active
040002756
ABSTRACT:
Benzimidazo[2,1-b]quinazolin-12(6H)ones, immunosuppressives and agents for treatment of auto-immune diseases, are prepared via (1) reacting a 2-chlorobenzimidazole with an anthranilic acid or ester; (2) reacting a 2-aminobenzimidazole with an anthranilic acid or ester in the presence of trifluoroacetic acid or (3) reacting a 2-methylmercaptobenzimidazole with an anthraniloyl halide hydrohalide.
REFERENCES:
camiener et al., Progress in Drug Research, vol. 16, pp. 113, 115, 116, 146, & 147.
Eli Lilly and Company
Rose Shep K.
Scanlon William B.
Smith Everet F.
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