Heterocyclic compounds and their preparation and use

Details Heterocyclic compounds and their preparation and use Heterocyclic compounds and their preparation and use

1997-04-17

2000-07-04

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514210, 514340, 514342, 546133, 5462687, 5462694, 540362, A61K 31439, C07D45300, C07D45302, C07D41704

Patent

active

060839570

ABSTRACT:
The present invention relates to therapeutically active quaternary azacyclic or azabicyclic compounds with formula I: ##STR1## wherein X is oxygen or sulfur and wherein G is selected from the group of azacyclic or azabicyclic ring systems consisting of: ##STR2## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a cholinergic deficit in the peripheral system.

REFERENCES:
patent: 5041455 (1991-08-01), Sauerberg et al.
patent: 5260314 (1993-11-01), Sauerberg et al.
patent: 5488056 (1996-01-01), Bodick et al.
Saunders, J. et al, J. Med. Chem., 1990, 33, pp. 1128-1138.
Morrison, R.T. et al, Organic Chemistry, 4th edition, Allyn & Bacon Inc., 1983, p. 919.

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