DNA encoding an interleukin-6 splice variant

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4352523, 4353201, 435325, 4353651, 435358, 435419, 435348, 536 235, 530351, C12N 1524, C07K 1454

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056416571

ABSTRACT:
Polynucleotides which encode the polypeptide IL-6SV, as well as such polypeptides, antibodies and antagonist inhibitors against the polypeptide and the use of the polypeptide as a pharmaceutical for treating cancer, auto-immune diseases, platelet reducing conditions, anemias, bone marrow and organ transplantation.

REFERENCES:
Yasukawa et al (1987) The EMBO Journal, 6:2939-2945.
Haegeman et al (1986) Eur. J. Biochem 159:625-632.
Hivano et al (1986) Nature 324:73-76.
Zilberstein et al (1986) The EMBO Journal 5:2529-2537.

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