Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-06-26
2000-07-04
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435206, 435183, 435195, 435200, 4352523, 4353201, 435325, 536 231, 536 232, C12N 914, C12N 924, C12N 936
Patent
active
060837004
ABSTRACT:
The invention provides a human goose-type lysozyme (GOLY) and polynucleotides which identify and encode GOLY. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GOLY.
REFERENCES:
Online Mendelian Inheritance in Man (OMIM) #153450 Lysozyme, Jun. 7, 1996.
Weaver, L.H. et al., "Structure of Phage P22 Gene 19 Lysozyme Inferred from its Homology with Phage T4 Lysozyme Implications for Lysozyme Evolution", J. Mol. Biol., 184: 739-741 (1985).
Nakano, T. and T. Graf, "Goose-type lysozyme gene of the chicken: sequence, genomic organization and expression reveals major differences to chicken-type lysozyme gene", Biochim. Biophys. Acta, 1090: 273-276 (1991).
Graf, T., (Direct Submission), GenBank Sequence Database (Accession X61002), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 63427; GI 63428) Apr. 13, 1992.
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Hagenbuchle and Wellauer, Nucleic Acids Research vol. 20(14): 3555-3559. 1992.
Corley Neil C.
Guegler Karl J.
Lal Preeti
Patterson Chandra
Incyte Pharmaceuticals Inc.
Prouty Rebecca E.
Rao Manjunath
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