Preparation of 2-alkylpyrimidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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C07D23926

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044939299

ABSTRACT:
2-Alkylpyrimidines are obtained in a one step reaction which comprises the dehydrogenation of a 2-alkyltetrahydropyrimidine over a supported noble metal catalyst under conditions which do not generate water and in which no water is added.

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Tsuchiya, et al., Chemical Abstracts, vol. 87, 84049e (1977).
Lythgoe, et al., J. Chem. Soc. 1951, pp. 2323-2329 (1951).
"The Pyrimidines", Interscience Publishers (1962), pp. 445-448, 455.
Okada, et al., Chemical Abstracts, vol. 85, 14225lm (1976).
Tsuchiya, et al., Chemical Abstracts, vol. 86, 29475h (1977).
Disteldorf, et al., Chemical Abstracts, vol. 89, 180044m (1978).

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