Process for the preparation of nucleosides

Details Process for the preparation of nucleosides Process for the preparation of nucleosides

1978-12-20

1980-06-24

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 1700

Patent

active

042096138

ABSTRACT:
In a process for preparing a nucleoside by silylating the corresponding nucleoside base and reacting the silylated base with a 1-O-acyl, 1-O-alkyl, or 1-halogen derivative of a blocked monosaccharide or oligosaccharide in the presence of a catalyst, an improvement comprises silylating the base and reacting the sugar derivative in a single step.

REFERENCES:
patent: 3352849 (1967-11-01), Shen et al.
patent: 3354160 (1967-11-01), Duschinsky et al.
patent: 3531464 (1970-09-01), Ryan et al.
patent: 3708469 (1973-01-01), Vorbruggen et al.
patent: 3748320 (1973-07-01), Vorbruggen et al.
patent: 3817980 (1974-06-01), Vorbruggen et al.
patent: 4082911 (1978-04-01), Vorbruggen
Wittenburg, E., Chem. Ber. 101, 1095-1114 (1968).
Wittenburg, E., Z. Chem. 4, Jg. (1964), Hept8,303.

Affiliated with

Also associated with

Rating

Process for the preparation of nucleosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of nucleosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of nucleosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1481389