Process for producing new antitumor anthracycline antibiotics

Details Process for producing new antitumor anthracycline antibiotics Process for producing new antitumor anthracycline antibiotics

1978-07-27

1980-06-24

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435189, 435888, 435886, C12P 1956

Patent

active

042095883

ABSTRACT:
New anthracycline glycosides designated MA 144-G1, -G2, -L,-S1, -N1, -U1 and -Y which inhibit the growth of gram-positive bacteria and mammalian tumors are produced by fermentation of certain species of Streptomyces and by the chemical or enzymatic conversion of certain anthracycline glycosides. New microbiological and chemical processes are also provided for preparation of the anthracycline glycosides MA 144-S2 and -U2 which have been found to be identical with the previously reported anthracyclines, marcellomycin and musettamycin.

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