Derivatives of steroid compounds linked to cyotoxic agents

Details Derivatives of steroid compounds linked to cyotoxic agents Derivatives of steroid compounds linked to cyotoxic agents

1984-02-15

1985-12-24

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603971, 2603975, C07J 700

Patent

active

045605122

ABSTRACT:
The present application is concerned with compounds useful as carriers of cytotoxic agents. More particularly it deals with derivatives of steroid compounds having a 5-androstene carbon skeleton and having an oleyl ester at the 3-position and having a 17-carbamyl alkyl substituent which linked to cytotoxic agents for delivery to cancer cells exclusively via the low-density lipoprotein (LDL) pathway.

REFERENCES:
patent: 4104285 (1978-08-01), Torres et al.
patent: 4372888 (1983-02-01), Hjelmeland
J. Med. Chem. (1984) 27(8) pp. 1037-1043, an article by Firestone et al.

Affiliated with

Also associated with

Rating

Derivatives of steroid compounds linked to cyotoxic agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Derivatives of steroid compounds linked to cyotoxic agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Derivatives of steroid compounds linked to cyotoxic agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1478157