Method of producing shikonin

Details Method of producing shikonin Method of producing shikonin

1984-03-26

1985-12-24

Hollrah, Glennon H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260396K, C07C 5014, C07C 5012

Patent

active

045605114

ABSTRACT:
A method of producing shikonin, having the following chemical structure ##STR1## which method comprises dehydrating 2-(1'-acetoxy-4'-hydroxy-4'-methylpentyl)-5,8-diacetoxy-1,4-naphthoquinone , treating the resulting product with an alkali hydroxide and acidifying the treated product.

REFERENCES:
patent: 4282250 (1981-08-01), Papageorgiou
Tetrahedron Letters, No. 19(1959) pp. 9-13, Farina, "A New Method for the Preparation of Naphtozorims."
Patai, The Chemistry of the Quinonoid Compounds, part 1, 1974, p. 134.
Y. N. Shukla et al., Experientia 25, 357 (1969).
U. Sankawa et al., Chem. Pharm. Bull. (Tokyo) 25, (9), 2392-2395 (1977).
U. Sankawa et al., Chem. Pharm. Bull. (Tokyo) 29, (1) 116-122, (1981).
M. Tabata et al., Abstract of Papers, 100th Annual Meeting of Pharm. Society of Japan (1980) p. 249.

Affiliated with

Also associated with

Rating

Method of producing shikonin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of producing shikonin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of producing shikonin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1478147