Human growth hormone formulation

Details Human growth hormone formulation Human growth hormone formulation

1988-04-15

1992-03-17

Moezie, F. T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514970, 514975, 514 21, 424 43, A61K 3736

Patent

active

050968858

ABSTRACT:
A stable pharmaceutically acceptable formulation containing human growth hormone, glycine, mannitol, a buffer, and optionally, a non-ionic surfactant is disclosed. The formulation contains human growth-hormone: glycine in 1:50-200 molar ratios. Also disclosed are associated means and methods for preparing and using such formulations.

REFERENCES:
patent: 4297344 (1981-10-01), Schwinn
patent: 4783441 (1988-11-01), Thurow
patent: 4812557 (1989-03-01), Yasushi
Becker et al., Biotechnology & Applied Biochemistry 9, 478-487 (1987).

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