Method and kit for detecting human exposure to genotoxic agents

Details Method and kit for detecting human exposure to genotoxic agents Method and kit for detecting human exposure to genotoxic agents

1988-12-27

1992-03-17

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

436501, 436536, 436813, 436815, 436 64, 436822, 435 71, C12Q 168, G01N 3353

Patent

active

050968084

ABSTRACT:
The present invention discloses a method and a kit for monitoring human exposure to genotoxic agents. The method comprises an immunoassay for detecting in human serum specific antibodies against DNA adducted to an agent suspected of being genotoxic. A kit comprising various components for performing the assay is also disclosed.

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Alarcon-Segovia, D., Mayo Clin. Proc. 44:664-681 (1969).
Dubroff, L., et al., Science 208:404-406 (1980).

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