Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-12-20
1995-01-24
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142358, 514252, 514255, 514212, 544 60, 544121, 544357, 544360, 544372, 544391, 540598, A61K 31495, A61K 3154, C07D295182, C07D295192
Patent
active
053843193
ABSTRACT:
Aminoalkylphenyl derivatives of formula I ##STR1## wherein alk, R.sub.1 -R.sub.6, X and Y are as defined in the description, and salts thereof, exhibit properties inhibiting the biosynthesis of interleukin-1 (IL-1) and analgesic properties and can therefore be used as active ingredients in medicaments. They are prepared in a manner known per se.
REFERENCES:
patent: 3926961 (1975-12-01), Ferrini et al.
patent: 4505913 (1985-03-01), Ferrini et al.
patent: 4804661 (1989-02-01), Ferrini et al.
patent: 5011928 (1991-04-01), Venero
patent: 5286728 (1994-02-01), Ferrini
patent: 5321027 (1994-06-01), Ferrini et al.
Kmonicek et al, Collect Czech. Chem. Commun., 55, pp. 1817-1827 (1990).
Derwent Abstract 91-134394/19 corresponding to EP 425,921-A, Published May 8, 1991.
Derwent Abstract 90-290298/38 corresponding to WO 9009-997-A, Published Sep. 7, 1990; filed Feb. 23, 1989.
Chem Abstr. 58, 10211 (1963), Jacob et al.
J. Med Chem 26(1983) 1065-1070; Metz et al "Cloxacepride and Related Compounds . . . ".
J. Med Chem 33 (1990) 2883-91; Lis et al, "Synthesis of (Aryloxy)propanolamines and Related Compounds . . . ".
Chem Abstr. 100, 174, 780c (1984), Agarwal et al.
Derwent Abstr 87-357055/51 corresponding to EP 250,361 (1986).
Chem Abstr. 112, 235261f (1990), Botros et al.
Chem Abstr. 87, 52957 h (1977), Liebenow et al.
Chem Abstr. 56, 10165c (1962), Jacob et al.
Chem Abstr. 57, 15126h (1962), Jacob et al.
Chem Abstr. 58, 3444e (1963), Jacob et al.
Chem Abstr. 58, 4583f (1963), Rhone-Poulec.
Bernhardt Emily
Ciba-Geigy Corporation
Fishman Irving M.
Kaiser Karen G.
LandOfFree
Aminoalkylphenyl compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aminoalkylphenyl compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminoalkylphenyl compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1468753