Hypoglycemic 5-substituted oxazolidine-2,4-diones

Details Hypoglycemic 5-substituted oxazolidine-2,4-diones Hypoglycemic 5-substituted oxazolidine-2,4-diones

1981-04-23

1982-08-03

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546152, 546334, 546340, 546275, 548214, 548240, 424258, C07D41304, A61K 3144

Patent

active

043427715

ABSTRACT:
Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

REFERENCES:
patent: 2338220 (1944-01-01), Wallingford
patent: 2721197 (1955-08-01), Sheehan
patent: 3699229 (1972-10-01), Plotnikoff
patent: 4220787 (1980-09-01), Scholz
Ciamacian and Silber, Ber. 19, pp. 1708-1714 (1886).
Clark-Lewis, Chem. Rev. 58, pp. 63-99 (1958).
Brink and Freeman, J. Neuro. Chem. 19 (7), pp. 1783-1788 (1972).

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