Production of m-fluoroacetophenone

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568312, 568323, C07C 49303

Patent

active

044879695

ABSTRACT:
A process for the production of m-fluoroacetophenone comprises reacting m-aminoacetophenone with a diazotization agent in the presence of hydrogen fluoride. The diazonium fluoride compound produced is decomposed by heating to produce highly pure m-fluoroacetophenone in good yields.

REFERENCES:
patent: 3954734 (1976-05-01), Doub et al.
patent: 4075252 (1978-02-01), Boudakian
Evans et al., "J. Chemical Society", (1935), pp. 1167-1173.
Taft et al., "J. American Chemical Society", (1963), vol. 85, pp. 709-724.
Zweig et al., "J. Organic Chemistry", (1980), vol. 3597-3503.

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