Antitumor tetracyclic compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D48700

Patent

active

060138076

ABSTRACT:
The present invention relates to heterocyclic compounds which have been found to have anti-tumour activity. More specifically, the invention concerns pyrrolo[2,3-b]carbazoles and 1H-[1] benzothieno [2,3-f] indoles, methods for their preparation, pharmaceutical formulations containing them and their use as anti-tumour agents. The compounds have low toxicity against normal cell lines whilst exhibiting anti-tumour cell activity.

REFERENCES:
patent: 3873528 (1975-03-01), Kuhlthau
patent: 4021451 (1977-05-01), Dobson et al.
patent: 4362739 (1982-12-01), Kuehne

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