Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1983-05-09
1984-12-11
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602457, 42424854, 424267, 424274, 544 585, 544142, 546199, 548422, A61K 3140, C07D40304
Patent
active
044877692
ABSTRACT:
Mitomycin A, mitomycin C, and porfiromycin react with amide acetals and other amide derivatives to produce amidine derivatives having antitumor activity against experimental animal tumors. The amidines derived from mitomycin C are useful intermediates in reactions with primary amines to produce both known and novel 7-amino-9a-methoxymitosanes having antitumor activity against experimental animal tumors.
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Doyle Terrence W.
Kaneko Takushi
Vyas Dolatrai M.
Bristol-Myers Company
Carnahan Robert E.
Raymond Richard L.
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