Endotoxins

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 14325

Patent

active

057601810

ABSTRACT:
Novel transformation vectors containing novel chimeric genes allow the introduction of exogenous DNA fragments coding for polypeptide toxins produced by Bacillus thuringiensis or having substantial sequence homology to a gene coding for a polypeptide toxin as described herein and expression of the chimeric gene in plant cells and their progeny after integration into the plant cell genome. Transformed plant cells and their progeny exhibit stably inherited polypeptide toxin expression useful for protecting said plant cells and their progeny against certain insect pests and in controlling said insect pests.

REFERENCES:
patent: 5010001 (1991-04-01), Pollock
patent: 5110905 (1992-05-01), Witt et al.
Applied and Environmental Microbiology, "Only Part of the Protoxin Gene of Bacillus thuringiensis subsp. Berliner 1715 is Necessary for Insecticidal Activity", H. Wabiko, et al., Mar. 1985, pp. 706-708.
DNA, "Bacillus thuringiensis Entomocidal Protoxin Gene Sequence and Gene Product Analysis", H. Wabiko, et al., vol. 5, No. 4, 1986, pp. 305-314.
Proc. Natl. Acad. Sci., "DNA Sequencing with Chain-Terminating Inhibitors", F. Sanger, et al., vo. 74, No. 12, pp. 5463-5467.
Rekombinierte DNA, James D. Watson, Chapter XIII, pp. 139-148, (1983).
Biotechnology and Genetic Engineering Reviews, "The Insecticidal Crystal Proteins of Bacillus thuringiensis: Past, Present and Future Uses", M. Koziel, et al., vol. 11, Dec. 1993, pp. 171-174.
D4-Restriction Map.
Chemical and Enzymatic Synthesis of Gene Fragments, A Laboratory Manual, edited by H.G. Gassen, 1982.
The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, Tenth Edition, 1983, p. 135.
The Journal of Biological Chemistry, "The Amino Acid Sequence of a Crystal Protein from Bacillus thuringiensis Deduced from the DNA Base Sequence", H. Schnepf, et al., vol. 260, No. 10, May 25, 1985, pp. 6264-6272.
The Journal of Biological Chemistry, "Delineation of a Toxin-Encoding Segment of a Bacillus thuringiensis Crystal Protein Gene", H. Schnepf, et al., vol. 260, No. 10, May 25, 1985, pp. 6273-6280.
Gene, "Nucleotide Sequence Coding for the Insecticidal Fragment of the Bacillus thuringiensis Crystal Protein", Y. Shibano, et al., vol. 34, 1985, pp. 243-251.
Bacillus thuringiensis: Microbiological 1532 Considerations, M. Rogoff et al., 1969, pp. 357-386.
Molecular Biology of Microbial Differentiation, Proceedings of the Ninth International Spore Conference, Asilomar, California, H.R. Whitely et al., 3-6 Sep. 1984.
Journal of Invertebrate Pathology, "The Insecticidal Crystal Protein CrylA(c) from Bacillus thuringiensis is Highly Toxic for Heliothis amigera", vol. 59, pp. 109-112, 1992.
Nature, "Transgenic Plants Protected from Insect Attack", vol. 328, Jul. 2, 1987.
Plant Physiol, "Bacillus thuringiensis .delta.-Endotoxins Expressed in Transgenic Nicotiana tabacum Provides Resistance to Lepidopteran Insects", (1987) 85, pp. 1103-1109.
Science, "Gene Transfer in Crop Improvements", vol. 236, pp. 48-54 Apr. 3, 1987.
The EMBO Journal, "Protein Fusions with the Kanamycin Resistance Gene from Transposon Tn5", vol. 3, No. 13, pp. 3317-3322, 1984.
Gene, "Characterized Full-Length and Truncated Plasmid Clones of the Crystal Protein of Bacillus thuringienus subsp. kurstaki HD-73 and Their Toxicity to Manduca sexta", 36 (1985) 289-300.
The EMBO Journal, "An Agrobacterium-Transformed Cell Culture from the Monocot Asparagus Officinalis", vol. 3, No. 13, pp. 3039-3041, 1984.
Bio/Technology, "Field Performance of Transgenic Tomato Plants Expressing the Bacillus thuringiensis Var. Kurstaki Insect Control Protein", vol. 7, pp. 1265-1268, 1989.,
Abstract of First International Congress, Plant Molecular Biology, Savannah, GA Oct. 1985.
Microbiological Reviews, "Insecticidal Crystal Proteins of Bacillus thuringiensis", pp. 242-255, Jun. 1989.
The Journal of Biological Chemistry, "Delineation of a Toxin-Encoding Segment of a Bacillus thuringiensis Crystal Protein Gene", vol. 260, No. 10, pp. 6273-6280.
The Journal of Bacteriology, "Structural Similarity Between the Lepidoptera-and Diptera-Specific Insecticidal Endotoxin Genes of Bacillus thuringiensis subsp. kurstaki and insraelensis", vol. 166, No. 3, pp. 801-811, Jun. 1986.
Biotechnology, "Insect Tolerant Transgenic Tomato Plants", vol. 5, pp. 807-813, 1987.
Proc. Natl. Acad. Sci., "Expression of Bacterial Genes in Plant Cells", vol. 80, pp. 4803-4807, Aug. 1983.
The EMBO Journal, "Chloroplast Transformation by Agrobacterium Tumefaciens", vol. 4, No. 6, pp. 1367-1372, 1985.
"A Bifunctional Gene for Insecticide and Kanamycin Resistance," Washington University School of Medicine.
Nature, "Expression of Ti Plasmid Genes in Monocotyledonous Plants Infected with Agrobacterium Tumefaciens", vol. 311, pp. 763-764, Oct. 1984.
The EMBO Journal, "High Level Expression of Introduced Chimaeric Genes in Regenerated Transformed Plants", vol. 4, No. 10, pp. 2411-2418, 1985.
Cell, "Integration and Organization of Ti Plasmid Sequences in Crown Gall Tumors", vol. 19, pp. 729-739, Mar. 1980.
The EMBO Journal, "Cloning and Expression of the Crystal Protein Genes from Bacillus thuringiensis Strain Berliner 1715", vol. 1, No. 7, pp. 791-799, 1982.
The EMBO Journal, "Expression of Foreign Genes in Regenerated Plants and in Their Progeny", vol. 3, No. 8, pp. 1681-1689, 1984.
Plant Physiol., "Transformation of Zea Mays L. Using Agrobacterium Tumefaciens and the Shoot Apex", vol. 95, pp. 426-434, 1991.
"Fifth Annual Meeting of the International Program on Rice Biotechnology", Oct. 2-5, 1991.
"Research Paper/Agrobacterium-Mediated Transformation of Rice (Oryza Sativa L.)", University of Washintong.
Genetics in Relation to Insect Management, "Genetic Manipulation of Pathogens; Selection of Different Strains", Dulmage, H.T., The Rockefeller Foundation, pp. 116-127 (1979).
Microbial Control of Pests and Plant Diseases 1970-1980, "Insecticidal Activity of Isolates of Bacillus thuringiensis and Their Potential for Pest Control", Dulmage, H.T., pp. 193-222 (1981).
Microbial Control of Insects and Mites, "Determination and Significance of the Host Spectrum of Bacillus thuringiensis", Burgerjon, A. et al., pp. 305-325 (1971).
Nucleic Acids Research, "Efficient Octopine Ti Plasmid-Derived Vectors for Agrobacterium-Mediated Gene Transfer to Plants", vol. 13, No. 13, pp. 4777-4788, 1985.
Agric. Biol. Chem., "A Toxic Fragment from the Entomocidal Crystal Protein of Bacillus thuringiensis", vol. 48, No. 3, pp. 611-619, 1984.
Journal of Molecular and Applied Genetics, "A Cauliflower Mosaic Virus Promoter Directs Expression of Kanamycin Resistance in Morphogenic Transformed Plant Cells", vol. 2, No. 6, pp. 549-562, 1984.
Journal of Molecular and Applied Genetics, "Site-Specific Mutagenesis of Agrobacterium Ti Plasmids and Transfer of Genes to Plant Cells", vol. 1, No. 2, pp. 149-164, 1981.
Journal of Molecular and Applied Genetics, "Nucleotide Sequence and Transcript Map of the Agrobacterium tumefaciens Ti Plasmid-Encoded Octopine Synthase Gene", vol. 1, No. 6, pp. 499-511, 1982.
Journal of Bacteriology, "Comparative Biochemistry of Entomocidal Parasporal Crystals of Selected Bacillus thuringiensis Strains", vol. 145, No. 2, pp. 1052-1062, Feb. 1981.
Proc. R. Soc. Lond., "Interactions and DNA Transfer Between Agrobacterium tumefaciens, the Ti-Plasmid and the Plant Host", vol. 204, pp. 251-266, 1979.
Proc. Natl. Acad. Sci., "Cloning and Localization of the Lepidopteran Protoxin Gene of Bacillus thuringiensis subsp. kurstaki", vol. 79, pp. 6065-6069, 1982.
Microbial Control of Pests and Plant Diseases 1970-1980, "Susceptibility of Arthropod Species to Bacillus thuringiensis ", Appendix 1, 1981, pp. 837-896.
CRC Critical Reviews in Microbiology, "Ultrastructure, Physiology, and Biochemistry of Bacillus thuringiensis",Oct. 1980, pp. 147-204.
Proc. Natl. Acd. Sci., "Cloning and Expression of the Bacillus thuringiensis Crystal Protein Gene in Escherichia coli", vol. 78, No. 5, May 1981, pp. 2893-2897.
Genetics and Biotechnology of Bacilli, "Structural and Regulatory Analysis of a Cloned Bacillus thuringiensis Crystal Protein Gene", 1984, pp. 375-386.
App

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Endotoxins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Endotoxins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Endotoxins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1461102

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.