Methods of preparing polymeric microbeds

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Cellular products or processes of preparing a cellular...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

521 62, 521 63, 521 64, 521 65, 521 69, 521146, 521147, 521150, 521902, 524733, C08J 926, C08J 928, C08J 930

Patent

active

057600970

ABSTRACT:
The present invention relates to porous crosslinked polymeric microbeads having cavities joined by interconnecting pores wherein at least some of the cavities at the interior of each microbead communicate with the surface of the microbead. The present invention also relates to a process for producing a porous, crosslinked polymeric microbead as well as the product of this process. This process involves combining an oil phase with an aqueous discontinuous phase to form an emulsion, adding the emulsion to an aqueous suspension medium to form an oil-in-water suspension of dispersed emulsion droplets, and polymerizing the emulsion droplets to form microbeads. At least 10% of the microbeads produced in accordance with the present invention are substantially spherical or substantially ellipsoidal or a combination of the two.

REFERENCES:
patent: 3255127 (1966-06-01), von Bonin
patent: 3822224 (1974-07-01), Gillan et al.
patent: 3879314 (1975-04-01), Gunning et al.
patent: 3891577 (1975-06-01), Kershaw et al.
patent: 3923704 (1975-12-01), Gunning et al.
patent: 3933579 (1976-01-01), Kershaw et al.
patent: 3988508 (1976-10-01), Lissant
patent: 4137380 (1979-01-01), Gunning et al.
patent: 4321332 (1982-03-01), Beresford et al.
patent: 4522953 (1985-06-01), Barby et al.
patent: 4536521 (1985-08-01), Haq
patent: 4611014 (1986-09-01), Jomes et al.
patent: 4612334 (1986-09-01), Jones et al.
patent: 4629742 (1986-12-01), Brady et al.
patent: 4742086 (1988-05-01), Masamizu et al.
patent: 4775655 (1988-10-01), Edwards et al.
patent: 4788225 (1988-11-01), Edwards et al.
patent: 4965289 (1990-10-01), Sherrington et al.
patent: 4985468 (1991-01-01), Elmes et al.
patent: 5147345 (1992-09-01), Young et al.
patent: 5149720 (1992-09-01), DesMarias et al.
patent: 5189070 (1993-02-01), Brownscombe et al.
patent: 5200433 (1993-04-01), Beshouri
patent: 5252619 (1993-10-01), Brownscombe et al.
patent: 5268097 (1993-12-01), Girot et al.
patent: 5306733 (1994-04-01), Adamski et al.
patent: 5306734 (1994-04-01), Bass et al.
patent: 5318554 (1994-06-01), Young et al.
patent: 5331015 (1994-07-01), DesMarais et al.
patent: 5583162 (1996-12-01), Li et al.
patent: 5653922 (1997-08-01), Li et al.
Arshady, R., "Suspension, Emulsion, and Dispersion Polymerization: A Methodological Survey," 270 Colloid & Polymer Science 717-732 (1992).
Even, W. and Gregory, D., "Emulsion-Derived Foams: Preparation, Properties, and Application," MRS Bulletin 29-33 (Apr. 1994).
Hainey, P. et al., "Synthesis and Ultrastructural Studies of Styrene-Divinylbenzene Polyhipe Polymers," 24 Macromolecules 117-121 (1991).
Lee, D. et al., "High Density BHK Culture Using Porous Microcarriers," Production of Biologicals from Animal Cell Culture, Butterworth-Heinemann 480-487 (1992).
Lee, D. et al., "Polystyrene Macroporous Bead Support for Mammalian Cell Culture," 665 Annals New York Academy of Sciences 137-145 (1992).
Small, P. and Sherrington, D., "Design and Application of a New Rigid Support for High Efficiency Continuous-flow Peptide Synthesis," 21 Journal of the Chemical Society 1589-1591 (1989).
Tijssen, P., "Nature of Protein-Plastic Interaction," Practice & Theory of Enzyme Immunoassays 298-314 (Elsevier 1985).
Williams, J., "Toroidal Microstructures from Water-in-Oil Emulsions," 4 Langmuir 44-49 (1988).
Williams, J. and Wrobleski, D., "Spatial Distribution of the Phases in Water-in-Oil Emulsions. Open and Closed Microcellular Foams from Cross-Linked Polystyrene," 4 Langmuir 656-662 (1987).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods of preparing polymeric microbeds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of preparing polymeric microbeds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of preparing polymeric microbeds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1460448

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.