Pharmaceutical formulations for parenteral use

Details Pharmaceutical formulations for parenteral use Pharmaceutical formulations for parenteral use

1989-12-11

1991-06-18

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536103, 424 11, 424 858, 424 941, 514777, 514937, C08B 3716, A61K 31735

Patent

active

050249983

ABSTRACT:
Aqueous parenteral solutions of drugs which are insoluble or only sparingly soluble in water and/or which are unstable in water, combined with cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin, provide a means for alleviating problems associated with drug precipitation at the injection site and/or in the lungs or other organs following parenteral administration.

REFERENCES:
patent: 3459731 (1969-08-01), Gramera et al.
patent: 4024223 (1977-05-01), Noda et al.
patent: 4228160 (1980-10-01), Szejtli et al.
patent: 4232009 (1980-11-01), Hayashi et al.
patent: 4351846 (1982-09-01), Matsumoto et al.
patent: 4352793 (1982-10-01), Yamahira et al.
patent: 4383992 (1983-05-01), Lipari
patent: 4407795 (1983-10-01), Nicolau
patent: 4424209 (1984-01-01), Tuttle
patent: 4425336 (1984-01-01), Tuttle
patent: 4438106 (1984-03-01), Wagu et al.
patent: 4474811 (1984-10-01), Matsuda et al.
patent: 4478995 (1984-10-01), Shinoda et al.
patent: 4479932 (1984-10-01), Bodor
patent: 4479944 (1984-10-01), Hayashi et al.
patent: 4479966 (1984-10-01), Hayashi et al.
patent: 4497803 (1985-02-01), Harada et al.
patent: 4499085 (1985-02-01), Masuda
patent: 4518588 (1985-05-01), Szejtli et al.
patent: 4524068 (1985-06-01), Szejtli et al.
patent: 4540564 (1985-09-01), Bodor
patent: 4555504 (1985-11-01), Jones
patent: 4565807 (1986-01-01), Uekama et al.
patent: 4575548 (1986-03-01), Ueda et al.
patent: 4596795 (1986-06-01), Pitha
patent: 4598070 (1986-07-01), Ohwaki et al.
patent: 4599327 (1986-07-01), Nogradi et al.
patent: 4603123 (1986-07-01), Chiesi et al.
patent: 4608366 (1986-08-01), Hasegawa et al.
patent: 4617298 (1986-10-01), Bodor et al.
patent: 4623641 (1986-11-01), Szejtli et al.
patent: 4659696 (1987-04-01), Hirai et al.
patent: 4663316 (1987-05-01), Ninger et al.
patent: 4675395 (1987-06-01), Fukazawa et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4727079 (1988-02-01), Bodor
patent: 4728509 (1988-03-01), Shimizu et al.
patent: 4728510 (1988-03-01), Shibanai et al.
patent: 4751095 (1988-06-01), Karl et al.
patent: 4764604 (1988-08-01), Muller
patent: 4824850 (1989-04-01), Bodor
patent: 4829070 (1989-05-01), Bodor
patent: 4834985 (1989-05-01), Elger et al.
patent: 4888427 (1989-12-01), Bodor
Chemical Abstracts, 110, 101775b (Abstract of Japanese Kokai 88/218,663, published Sep. 12, 1988).
Irie et al., Pharmaceutical Research, vol. 5, No. 11, 1988, 713-717.
Yoshida et al., International Journal of Pharmaceutics, 46, 1988, 217-222.
Koizumi et al., Chem. Pharm. Bull., 35(8), 3413-3418 (1987).
Okada et al., Chem. Pharm. Bull., 36(6), 2176-2185 (1988).
Yamamoto et al., in International Journal of Pharmaceutics, 49, 163-171 (1981).
Brewster et al., J. Pharm. Sci., vol. 77, No. 11, Nov. 1988, 981-985.
Brewster et al., in Proceedings of the Fourth International Symposium on Cyclodextrins, Munich, 20th-22nd Apr., 1988, pp. 399-404, Kluwer Academic Publishers, Dordrecht, NL.
Pitha et al., in Controlled Drug Delivery, ed. S. D. Bruck, vol. I, CRC Press, Boca Raton, Fla., 125-148 (1983).
Uekama, Pharm. Int., Mar. 1985, 61-65.
Pitha, Journal of Inclusion Phenomena 2, 477-485 (1984).
Fenyvesi et al., Chem. Pharm. Bull. 32 (2), 665-669 (1984).
Uekama et al., International Journal of Pharmaceutics, 23, 35-42 (1985).
Pitha, J. Pharm. Sci., vol. 74, No. 9, Sep. 1985, 987-990.
Matsuyama et al., Drug Development and Industrial Pharmacy, 13(15), 2687-2691 (1987).
Pitha et al., International Journal of Pharmaceutics, 29, 73-82 (1986).
Uekama et al., in CRC Critical Reviews in Therapeutic Drug Carrier Systems, vol. 3(1), 1-40 (1987).
Uekama, in Topics in Pharmaceutical Sciences, 1987, eds. D. D. Breimer & P. Speiser Publishers, B.V. (Biomedical Division), 181-194 (1987).
Pagington, Chemistry in Britain, 455-458 (May 1987).
Carpenter et al., The Journal of Pediatrics, III, 507-512 (Oct. 1987).
Estes et al. in Biological Approaches to the Controlled Delivery of Drugs, ed. R. L. Juliano, Annals of the New York Academy of Sciences, vol. 907, 1987, 334-336.

Affiliated with

Also associated with

Rating

Pharmaceutical formulations for parenteral use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical formulations for parenteral use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical formulations for parenteral use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-145863