Production of human serum alubumin A

Details Production of human serum alubumin A Production of human serum alubumin A

1989-10-05

1998-06-02

Crouch, Deborah

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 698, 435 711, 4352552, 4353201, 935 11, 935 60, C12D 2106, C12D 2104, C12N 1500, C12N 114

Patent

active

057598029

ABSTRACT:
A process for the production of human serum albumin A (HSA) characterized by culturing host cells transformed with the plasmids containing a leader DNA sequence and a cDNA coding for mature HSA to produce and secrete mature HSA, and recovering the mature HSA. As the leader HSA sequence, a cDNA coding for the prepro sequence of HSA, a synthetic DNA coding for the prepro sequence of HSA, by the codons frequently used in a selected host, a DNA coding for a chimeric leader peptide, a DNA coding for MF.alpha.1 prepro sequence, or a DNA coding for PH05 signal peptide, is used.

REFERENCES:
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