Antagonists of gonadotropin releasing hormone

Details Antagonists of gonadotropin releasing hormone Antagonists of gonadotropin releasing hormone

1996-12-05

1998-12-15

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 514418, 514415, 514379, 514255, 514256, 514247, 514253, 544124, 544360, 544364, 5462774, 546157, 546122, 546176, 546193, 548455, A61K 3144, A61K 3140, C07D21512, C07D20902

Patent

active

058497641

ABSTRACT:
There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

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Medline 95188753, abstract of Polsker, Drugs, vol. 48(6), pp. 930-967, Dec. 1994.
Medline 95088771, abstract of Garner, Journal of Obstetric, Gynecologic, and Neonatal Nursing, vol. 23(7), pp. 563-570, Sep. 1994.

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