Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof,

Details Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof, Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof,

1996-03-15

1998-12-15

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 9, 530317, A61K 3800, A61K 3812, A61K 3808, C07K 764

Patent

active

058496920

ABSTRACT:
The invention relates to novel cyclopeptides of the formula I

REFERENCES:
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Mueller et al, Angewandte Chemie Int. Ed., vol. 31(3), (Mar. 1992), pp. 326-328.
Kumagai et al., Biochem. & Biophys. Res. Com., 177(1):74-82 (May 31, 1991).
Neubert et al., Pharmazie, 40, H. 8, pp. 532-535 (1985).
Smith et al., J. Biol. Chem., 265:12267-12271 (1990).
Chem. Abstracts, 119(5):49882d (Aug. 2, 1993).
Chem. Abstracts, 118(17):169613t (Apr. 26, 1993).
Neubert et al., "Synthese cyclischer under cyclisch-verzweigter . . .", Pharmazie 40 (1985), H. 8, pp. 532-535.
Smith et al., "Interaction of Integrins .alpha..sub.v .beta..sub.3 and Glycoprotein IIB . . ." J. Biol. Chem. 265, 12267-12271 (1990).

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