Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1982-03-29
1985-04-16
Love, Ethel G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
260112R, 435240, 435241, 536 28, 536 29, C07H 1512, C07H 1700
Patent
active
045117136
ABSTRACT:
A process for selectively controlling or interfering with the effect or function of foreign nucleic acid in the presence of otherwise normal living cells which comprises determining the base sequence for the nucleic acid and binding the nucleic acid with an appropriately prepared nonionic oligonucleoside alkyl or arylphosphonate analogue which is complementary to the indicated sequence of the foreign nucleic acid.
REFERENCES:
patent: 3560478 (1971-02-01), Myers
Chemical Abstracts 91: 205795p, (1979).
Jayaraman et al., Pra. Natl. Acad. Sci. U.S.A., vol. 78, No. 3, pp. 1537-1541, Mar. 1981.
Miller et al., Biochemistry, 1981, 20, 1874-1880.
Miller et al., Biochemistry, (1977), 16, 1988-1996.
Miller et al., Fed. Pro. Abst., 36,695, (1977), Abst. No. 2231.
Miller Paul S.
T'so Paul O. P.
Love Ethel G.
The Johns Hopkins University
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