Method of identifying agents that modulate UCP2 promoter activit

Details Method of identifying agents that modulate UCP2 promoter activit Method of identifying agents that modulate UCP2 promoter activit

1998-06-19

1998-12-15

McKelvey, Terry

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 6, C12Q 102, C12Q 168

Patent

active

058495142

ABSTRACT:
The invention relates to regulators of UCP2 gene transcription, including novel UCP2 transcriptional promoters. UCP2 gene promoters are used in diagnosis and pharmaceutical development. In particular, transfected cells comprising UCP2 gene promoters operably linked to a reporter are used in high-throughput pharmaceutical screens.

REFERENCES:
Fleury et al, Nature Genetics, vol. 15(3), pp. 269-272, Mar. 1997.

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