Synergistic anticancer combination

Details Synergistic anticancer combination Synergistic anticancer combination

1986-11-04

1990-01-09

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514283, A61K 3150, A61K 31495, A61K 3144

Patent

active

048928747

ABSTRACT:
It is disclosed that a compound having the formula ##STR1## or a pharmaceutically acceptable salt thereof in combination with vincristine produces synergistic antitumor activity.

REFERENCES:
patent: 4450160 (1984-05-01), Temple, Jr. et al.
Cancer Research, Nov., 1982, vol. 42, No. 11, pp. 4382-4386.
J. Med. Chem. Mar., 1980, vol. 23, No. 3, pp. 300-304.
Wheeler et al., Cancer Res., 43, 3567 (1983).
Temple et al., J. Med. Chem., 26, 91 (1983).
1986 AACR Abstract Form.

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