Heterocycle substituted propenoic acid derivatives as NMDA antag

Details Heterocycle substituted propenoic acid derivatives as NMDA antag Heterocycle substituted propenoic acid derivatives as NMDA antag

1997-12-15

1999-11-09

Fan, Jane

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, A61K 3144

Patent

active

059815531

ABSTRACT:
The present invention is new 3-(heterocyclic)-propenoic acid derivatives and pharmaceutical compositions thereof. These new 3-(heterocyclic)-propenoic acid derivatives are useful as NMDA antagonist.

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patent: 5714500 (1998-02-01), Griffith et al.
Salituro F.G. et al, Bioorganic & Medicinal Chem. Ltrs, vol. 1, No. 9 pp. 455-460, 1991.
Kemp, John A., TiPS--Jan. 1993, vol. 14, No. 1, pp. 20-25.
Schelkun, R.M. et Al, 33rd Nat'l Organic Chemistry Symposium Bozeman, MT--Jun., 1993 Abstract #B-73.
Thornber, Chemical Society Review, vol. 8, No. 4, 1979.

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