Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1995-06-07
1999-11-09
Degen, Nancy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
424 937, 435325, 514 2, 530399, C12Q 100, C12N 500, A61K 3830
Patent
active
059811650
ABSTRACT:
A culture method for inducing the expression of tyrosine hydroxylase in neural cells is provided. Mammalian CNS neural cells are cultured in the presence of a fibroblast growth factor and at least one selected from a member of the transforming growth factor beta family, a feeder layer bed of cells, and cell conditioned medium. Cells cultured as provided above may be transplanted to provide dopaminergic cells to a patient. The cells may also be used in methods for drug screening.
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Reynolds Brent
Weiss Samuel
Degen Nancy
NeuroSpheres Holdings Ltd.
Sandals William
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