Substituted and bridged pyridines useful as calcium channel bloc

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 43, 546 44, 546 39, 546 40, 546 63, 546 34, 544 61, 544125, 544361, 514222, 514236, 514253, 514279, 514281, 514286, A61K 3144, A61K 3147, C07D49108

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active

045993416

ABSTRACT:
Novel substituted and bridged pyridine compounds useful as calcium channel blockers, pharmaceutical compositions thereof, and methods of treatment are disclosed.

REFERENCES:
patent: 3466288 (1969-09-01), Hansen et al.
patent: 3518271 (1970-06-01), Shavel, Jr. et al.
patent: 4172201 (1979-10-01), Jarque et al.
patent: 4178450 (1979-12-01), Jarque et al.
Bossert et al., Angew. Chem. Int. Ed., vol. 20, pp. 762-769 (1981).
Schramm et al., Nature, vol. 309, pp. 535-537, (Jun. 9, 1983).

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