Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-07-16
1986-07-08
Tanenholtz, Alvin E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4351723, 435235, 435 6, 436536, 436538, 436547, 436804, 436813, 436823, 935 47, 935 60, 935 27, 530387, 530806, 530329, 530327, 530326, G01N 3353, C12N 1500
Patent
active
045993050
ABSTRACT:
A method for detecting chronic myelogenous leukemia in a human comprising the step of testing a biological sample from a patient to determine the presence of a marker protein (P210) which is characterized as a c-abl protein having tyrosine kinase activity and a molecular weight of approximately 210,000. Antisera which are specific for the P210 protein are disclosed which can be used to precipitate the P210 protein to allow identification by gel electrophoresis or other technique.
REFERENCES:
patent: 4100022 (1978-07-01), Ogasa et al.
patent: 4323546 (1982-04-01), Crockford et al.
patent: 4364936 (1982-12-01), Kung et al.
patent: 4379839 (1983-04-01), Spiegelman
Dale, B. et al., UCLA Symp. Mol. Cell. Biol. 5 in Tumor Viruses & Differentiation, Scolnick, E. M. et al. ed, Liss, NY (1983).
Groffen, J. et al., Nature, vol. 304, pp. 167-169, (1983).
Reynolds, F. H. et al., J. Virology, vol. 44(3), pp. 1097-1101, (1982).
Canaani, E., Lancet vol. 1 (8377), pp. 593-595, (1984).
Collins, S. J. et al., Science, vol. 225 (4657), pp. 72-74, (1984).
Collins, S. J. et al., Proc. Natl. Acad Sci, USA, vol. 80, pp. 4813-4817, (1983).
Witte, O. N. Current Topics in Microbiology, vol. 103, pp. 127-146, (1983).
Ponticelli, A. S. et al., Cell, vol. 29(3), pp. 953-960 (1982).
Bartram, C. R. et al., Nature, vol. 306, pp. 277-280, (11-1983).
Wang, J. Y. J. et al., Cell, vol. 36, pp. 349-356, (12-1984).
Heisterkamp, N. et al., Nature, vol. 306, pp. 239-242, (11-1983).
Whitlock, C. A. et al., Cell, vol. 32, pp. 903-911 (3-1983).
Jane, M. et al., Nature, vol. 300(5893), pp. 659-661 (12-1982).
Mushinski, J. F. et al., Science, vol. 220 (4599), pp. 795-798, (5-1983).
Reddy, E. P. et al., Proc. Natl. Acad. Sci, USA, vol. 80, pp. 3623-3627, (6-1983).
DeKlein, A. et al., Nature, vol. 300(5894), pp. 765-767, (12-1982).
Heisterkamp, N. et al., Nature, vol. 299(5885), pp. 747-749 (10-1982).
Whitlock, C. A. et al., Molecular & Cellular Biology, vol. 3,(4), pp. 596-604, (4-1983).
Goff, S. P. et al., Science, vol. 218, pp. 1317-1319 (12-1982).
Konopa, J. B. et al., Journal of Virology, vol. 51(1), pp. 223-232, (Jul. 1984).
Konopa, J. B. et al., Cell, vol. 37, pp. 1035-1042 (Jul. 1984).
Konopka James
Watanabe Susan
Witte Owen N.
Moskowitz M.
Tanenholtz Alvin E.
The Regents of the University of California
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