Diaryl piperidine containing esters of 1,4-dihydropyridines and

Details Diaryl piperidine containing esters of 1,4-dihydropyridines and Diaryl piperidine containing esters of 1,4-dihydropyridines and

1985-09-30

1987-11-17

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546193, 546194, A61K 31455, C07D40112, C07D41314

Patent

active

047074868

ABSTRACT:
Diaryl compounds of formula I ##STR1## wherein Ar represents a ring of the formula ##STR2## in which Y denotes oxygen (O), sulfur (S), vinylene (--CH.dbd.CH--), azomethine (--CH.dbd.N--) or a group of the formula ##STR3## R1, R2 and R3 are identical or different and denote hydrogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.7 -alkoxyalkyl, aryl, aryl-C.sub.1 -C.sub.6 -alkyl or aryloxy-C.sub.1 -C.sub.6 -alkyl,

REFERENCES:
patent: 4532248 (1985-07-01), Franckowink et al.
Burger, A., Medicinal Chemistry, second edition, 1960, Interscience Publishers, New York, pp. 566, 568, 580, 600, 601.
Thomas, G. et al., Journal of Cardiovascular Pharmacy, 6:1170-1176, 1984.

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