Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1997-03-19
1999-01-26
Redding, David A.
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
4353053, 4353054, C12M 300
Patent
active
058637923
ABSTRACT:
A multiwell tissue culture assembly for culturing cells comprising a plate and a lid. The plate includes a plurality of wells for accommodating a cell culture insert and the lid includes means for varying the gas diffusion into and out of the assembly and for substantially minimizing biological contamination of the cells being cultured in the cell culture insert. The means for varying the gas diffusion is a gas permeable membrane provided in a plurality of openings in the lid and a plurality of removable thin impermeable film labels are provided for selectively occluding passage of gases through the gas permeable membranes. The means for minimizing biological contamination of the cells being cultured is a sealing material located in the lid and means for removably securing the lid and the plate together whereby the sealing material is compressed between the lid and the plate.
REFERENCES:
patent: 1515016 (1924-11-01), Earp-Thomas
patent: 4657867 (1987-04-01), Guhl et al.
patent: 5358871 (1994-10-01), Stevens et al.
patent: 5417576 (1995-05-01), Hill
patent: 5571721 (1996-11-01), Turner
Barker Susan L.
Stevens Timothy A.
Tyndorf Tadeusz A.
Becton Dickson and Company
Redding David A.
Thomas Nanette S.
Weintraub Bruce S.
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