Human Protein Kinases

Details Human Protein Kinases Human Protein Kinases

1996-09-12

1999-01-26

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435325, 43525733, 4353201, 536 231, 536 232, 536 235, C12N 912, C07H 2104

Patent

active

058637800

ABSTRACT:
The present invention provides novel human protein kinases (HPK) and polynucleotides which identify and encode HPK. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HPK. The invention also provides for pharmaceutical compositions comprising HPK or antagonists of HPK, and antibodies which specifically bind HPK. Additionally, the invention provides antisense molecules to HPK for treatment or prevention of diseases associated with abnormal expression of HPK.

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Webster et al. "Characterization of sgk, a novel memmber of the serine/threonine protein kinase gene family . . . " Mol. Cell. Biol. 13(4), 20-31-2040, Apr. 1993.
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