N-substituted amino acid derivatives

Details N-substituted amino acid derivatives N-substituted amino acid derivatives

1975-10-02

1977-10-18

Thomas, Jr., James O.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424319, 260534R, 560170, 560172, C07C10128, C07C10348, A01N 924, A01N 930

Patent

active

040546683

ABSTRACT:
Novel N-substituted amino acid derivatives of the formula: ##STR1## wherein R.sub.1 is an alkenyl group having 2 to 5 carbon atoms, a halogen-substituted alkenyl group having 2 to 5 carbon atoms or an alkynyl group having 2 to 5 carbon atoms, R.sub.2 is a methyl or ##STR2## group in which R.sub.2 ' is an alkyl group having 1 to 4 carbon atoms or a halogen-substituted alkyl group having 1 to 4 carbon atoms; and R.sub.3 is a hydrogen atom, an alkyl having 1 to 20 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, benzyl, hydroxyethyl or methoxyethyl group, and inorganic or organic acid addition salts thereof, which possess useful soil fungicidal activities and can be produced by reacting a sarcosine derivative of the formula:

REFERENCES:
patent: 2700027 (1955-01-01), Bruson
patent: 2965534 (1960-12-01), Darlington
patent: 3238236 (1966-03-01), Hauptschein
Weygand, Preparative Organic Chemistry, pp. 448-461 & 468-472, 1972.
Morrison, Organic Chemistry, pp. 722, 743 & 744 (1966).
Speziale, J. Org. Chem., 25, pp. 728-732, (1960).
Supniewski, Chem. Abst., 22:666-3 (1927).

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