Pyridyl oxamic acid derivatives and use in the prevention of al

Details Pyridyl oxamic acid derivatives and use in the prevention of al Pyridyl oxamic acid derivatives and use in the prevention of al

Filed on

1976-03-23

Date issued

1977-10-18

Examiner

Drezin, Norman A.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Antigen, epitope, or other immunospecific immunoeffector

SubSubClass

Bacterium or component thereof or substance produced by said...

Other Related Categories

260295AM, 2602955A, A61K 3144, C07D21336

Type

Patent

Status

active

Patent number

040546616

Description

ABSTRACT:
Anti-allergic agents of aromatic and heterocyclic oxamic acid derivation present the following formula: ##STR1## in which A is a member selected from the group consisting of 2-thiazolyl, 2-pyridyl, 2-pyridyl-N-oxide, 6-(lower)alkyl-2-pyridyl, 3-cyano-2-pyridyl, 3-pyridyl, 4-pyridyl, 2-pyrimidinyl, 2-pyrazinyl, .alpha.-naphthyl, .beta.naphthyl, phenyl, 2,6-dichlorophenyl, and substituted phenyl moieties containing from one to three substituents in any of the 2,3,4 and 5 positions of the phenyl ring, independently selected from the group consisting of lower alkyl, lower alkylthio, lower alkylsulfinyl, lower alkoxy, hydroxy(lower)-alkoxy, 2-(lower alkoxy oxalyloxy) ethoxy, benzyloxy, N-mono-and di-lower alkylamino(lower)-alkoxy, halo, sulfamyl, polyhalo(lower)alkyl, carbamyl, N-lower alkylcarbamyl, nitro, mono-and di-lower alkylamino, phenylazo, carboxy, lower alkylcarbonyl, cyano, carb(lower)alkoxy, phenoxy(lower)alkoxy, lower alkoxyoxalamido and lower alkoxyoxalamidophenoxy radicals;

REFERENCES:
petyunin et al., Journal of General Chemistry-USSR, 34(1), pp. 26-30, (1964).
Petyunin et al., Journal of General Chemistry-USSR, 32(1), pp. 1383-1385, (1962).

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