Process for preparing N-mono(alkoxymethyl) phenobarbitals

Details Process for preparing N-mono(alkoxymethyl) phenobarbitals Process for preparing N-mono(alkoxymethyl) phenobarbitals

1975-09-24

1977-10-18

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D23962

Patent

active

040545652

ABSTRACT:
N-mono (alkoxymethyl)phenobarbitals wherein the alkoxy group has 1 to 4 carbon atoms are disclosed. The compounds are prepared by reacting the dialkali metal salt of thiophenobarbital with chloromethyl alkyl ether followed by treating the resultant N,S-bis(alkoxymethyl)thiophenobarbital with an oxidizing agent. The compounds are useful as anticonvulsant agents.

REFERENCES:
patent: 790116 (1905-05-01), Einhorn et al.
patent: 2445898 (1948-07-01), Wenner

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