Preservation of glucose in blood samples

Details Preservation of glucose in blood samples Preservation of glucose in blood samples

1976-02-26

1977-10-18

Marantz, Sidney

Textiles: fiber preparation

21 58, 23230B, 252408, G01N 3316

Patent

active

040544885

ABSTRACT:
A process and preservatives for preventing glycolysis in blood samples so as to preserve the glucose content and lactic acid content thereof. The preservatives do not produce any significant hemolysis in the blood sample, and they do not interfere with any of the known blood constituents. The preservatives comprise salts of Iodoacetic acid, such as Tris-Iodoacetate [(CH.sub.2 OH).sub.3 NH.sub.3 CO.sub.2 -- CH.sub.2 I]; salts of Bromoacetic acid, such as Tris-Bromoacetate [(CH.sub.2 OH).sub.3 NH.sub.3 CO.sub.2 -- CH.sub.2 Br], or Sodium Bromoacetate [NaO.sub.2 CCH.sub.2 Br]; and salts of mono Chloroacetic acid (ClCH.sub.2 COOH), such as Sodium Chloroacetate (NaO.sub.2 CCH.sub.2 Cl).

REFERENCES:
patent: 3629142 (1971-12-01), Marbach
patent: 3682835 (1972-08-01), Louderback
patent: 3847738 (1974-11-01), Brake
patent: 3859049 (1975-01-01), Ware
patent: 3873467 (1975-03-01), Hunt
patent: 3874384 (1975-04-01), Deindoerfer
White et al, Principles of Biochemistry, 4th Ed., 238-239, 398-399, McGraw-Hill, N. Y. (1968).
Chemical Abstracts, 78:157266z (1973).
Chemical Abstracts, 75:107198w (1971).
Chemical Abstracts, 70:56189f (1969).
Chemical Abstracts, 62:1222d (1965).

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