Prostaglandins of the F series

Details Prostaglandins of the F series Prostaglandins of the F series

1992-09-16

1993-06-22

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562503, C07C17700

Patent

active

052217639

ABSTRACT:
The present invention provides new compounds, 13,14-dihydro-15-keto-PGFs, and vassopressors containing them, which raise blood pressure without substantial ephemeral depression of blood pressure, trachea or enteron contraction effect inherent in usual PGFs.

REFERENCES:
patent: 4089885 (1978-05-01), Husbands
patent: 4128713 (1978-12-01), Schneider et al.
patent: 4131738 (1978-12-01), Smith
patent: 4306075 (1981-12-01), Aristoff
patent: 4306076 (1981-12-01), Nelson
Simon, Acta Physiol Acad Sci Hung. 60 205 1982 Abstract Only.
IRCS Med. Sci. Libr. Compend. 1981, 9 (4), 364 (C.A. 95,913597).
Agnew. Chemie 20, 12 (1981), 1046.
Acta Pharmaceutica Sinica, vol. 16, No. 5 (1981).
Biochem. Biophys. Acta, 917(3), 356-54 (1987).
Adv. Prostaglandin Thromboscane Res., 1 215-19 (1976).

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