Systems for the controlled release of macromolecules

Details Systems for the controlled release of macromolecules Systems for the controlled release of macromolecules

1981-08-10

1983-07-05

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 22, A61K 926, A61K 3174, A61K 3726

Patent

active

043917976

ABSTRACT:
Delivery systems manufactured in the form of polymeric compositions for the controlled delivery of macromolecules to environments of use are disclosed. The systems are characterized as two-phase compositions comprising a phase formed of an insoluble polymeric matrix having limited water sorptivity containing in admixture therein an interpenetrating phase formed of a particulate hydrophilic water swellable, biologically active macromolecular material.

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Chem. Abstracts 86, #13233d, #13234e, #13237h, #91290j, #67536y, #67983s, #116803u, (1977).
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Chem. Abstracts 77, #14570n (1972) of Davis, B. K., Experientia (1972) 28(3) 348, Control of Diabetes with Polyacrylamide Implants Cont'g Insulin.

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