Substituted phenyl-2-(1H)-pyrimidinones useful for treating card

Details Substituted phenyl-2-(1H)-pyrimidinones useful for treating card Substituted phenyl-2-(1H)-pyrimidinones useful for treating card

1984-04-17

1986-04-15

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544315, A61K 31505, C07D23902

Patent

active

045828342

ABSTRACT:
New substituted phenyl-2-(1H)-pyrimidinones of the general formula I ##STR1## in which R.sup.1 denotes an alkyl group having 1 to 4 carbon atoms, and R.sup.2 and R.sup.3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a hydroxyl group or an alkoxy group having 1 to 4 carbon atoms, it being possible for each alkyl moiety to be straight-chain or branched, and their tautomeric forms and their acid addition salts and N-oxides have a positive inotropic effect and can thus be used as medicaments for the treatment of cardiac insufficiency.

REFERENCES:
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Hubert-Habart et al., Chem. Abst. vol. 70-37765z.
Hubert-Habart et al., Chem. Abst. vol. 79-105183w.
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