Process for the preparation of adenine derivatives made function

Details Process for the preparation of adenine derivatives made function Process for the preparation of adenine derivatives made function

1975-04-29

1977-02-15

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

195 52, 536 29, C07H 1920

Patent

active

040083632

ABSTRACT:
Nicotinamide 6-(2-hydroxy-3-carboxy-propylamino) purine dinucleotide is prepared by reacting nicotinamide-adenine-dinucleotide with 3,4 epoxybutanoic acid in the presence of perchloric acid to prepare an intermediate wherein the adenine nucleus is alkylated in the N.sub.1 position. That intermediate is subjected to chemical reduction of the nicotinamide ring, followed by rearrangement to yield the end product wherein the amino group in position 6 of the adenine ring is alkylated.

REFERENCES:
patent: 3287352 (1966-11-01), Wiley
patent: 3475408 (1969-10-01), Kuhn et al.

Affiliated with

Also associated with

Rating

Process for the preparation of adenine derivatives made function does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of adenine derivatives made function, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of adenine derivatives made function will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1438373