.alpha.-Aryl-.alpha.,.alpha.-bis[.omega.-(disubstituted amino)al

Details .alpha.-Aryl-.alpha.,.alpha.-bis[.omega.-(disubstituted amino)al .alpha.-Aryl-.alpha.,.alpha.-bis[.omega.-(disubstituted amino)al

Filed on

1977-03-11

Date issued

1978-08-15

Examiner

Wyman, Daniel E.

Patent Class

Chemistry of carbon compounds

SubClass

Miscellaneous organic carbon compounds

SubSubClass

C-metal

Other Related Categories

260239BF, 260295AM, 26029369, 26029376, 26032643, 424244, 42424854, 424263, 424267, 424274, 424324, 544131, 544168, 544163, 544124, A61K 31165, C07C10328

Type

Patent

Status

active

Patent number

041072057

Description

ABSTRACT:
Novel .alpha.-aryl-.alpha.,.alpha.-bis[.omega.-(disubstituted amino)alkyl]acetamides are described herein. The compounds are useful as anti-arrhythmic agents. The compounds are prepared by reacting an appropriate disubstituted acetonitrile with an appropriate haloalkyl amine and subsequently hydrolyzing the resulting nitrile with concentrated sulfuric acid.

REFERENCES:
patent: 2884436 (1959-04-01), Janssen et al.
patent: 2894955 (1959-07-01), Aspergren et al.
patent: 3022314 (1962-02-01), Aspergren et al.
patent: 3078275 (1963-02-01), Moffett et al.
patent: 3225091 (1965-12-01), Ainsworth et al.
patent: 3344146 (1967-09-01), Casadio
Casadio et al., J. Med. Chem. 8 (5), 594-598 (1965).

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