Preparation of halogenated quinolonecarboxylic acids

Details Preparation of halogenated quinolonecarboxylic acids Preparation of halogenated quinolonecarboxylic acids

1985-07-12

1987-07-14

Rosen, Sam

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546156, 546157, C07D21516

Patent

active

046804013

ABSTRACT:
The invention is a process of making the compounds of the structure ##STR1## wherein R is alkyl with 1-3 carbon atoms, 2-fluoroethyl, phenyl or cyclopropyl, X is halogen, and X.sup.1 and X.sup.2 each independently is hydrogen or halogen. The compounds are useful as intermediates for quinoline antibacterial compounds.

REFERENCES:
patent: 4529725 (1985-07-01), Chu
patent: 4544658 (1985-10-01), Peterson
Erickson, J. Medicinal Chemistry 22(7), pp. 816-823 (1979).

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