6-(1-Hydroxyethyl)-2-(2-aminoeth ylthio)-1-substituted-1-carbade

Details 6-(1-Hydroxyethyl)-2-(2-aminoeth ylthio)-1-substituted-1-carbade 6-(1-Hydroxyethyl)-2-(2-aminoeth ylthio)-1-substituted-1-carbade

1978-10-24

1980-08-19

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

2602452T, 260239A, 260559T, 542413, 542416, 544 92, 560 16, 560 21, 560205, 560210, C07D48704, A61K 3140

Patent

active

042184622

ABSTRACT:
Disclosed are 1-substituted-6-(1-hydroxyethyl)-2-(2-aminoethylthio)-1-carbadethiapen-2-e m-3-carboxylic acids (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics; such compounds are prepared by total synthesis. ##STR1## wherein R.sup.1 is, inter alia, substituted and unsubstituted alkyl, aryl and aralkyl.

REFERENCES:
patent: 3950357 (1976-04-01), Kahan et al.
Johnston et al., J.A.C.S. p 313 (1978).

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