Utilization of otilonium bromide (DCI) for topical application i

Details Utilization of otilonium bromide (DCI) for topical application i Utilization of otilonium bromide (DCI) for topical application i

1987-11-04

1990-12-18

Dixon, Jr., William R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 46, 128 4, C07C22900

Patent

active

049787721

ABSTRACT:
Use of bromure d'otilonium, that it otilonii bromidum, for local applications in the gastrointestinal tract of the digestive system and related pharmaceutical formulation appropriate for such use, to obtain the arrest of the motility of the gastrointestinal tract in order to allow endoscopic manoeuvers for diagnostic and therapeutic purposes.

REFERENCES:
Maggi et al., "Assessment of Potential Selectively of Antispasmodics for the Various Sections of the Gastrointestinal Tract of the Rat As A Guideline for Their Clinical Use", Arch. Int. Pharmacodyn. Thes., 262(2), pp. 221-230, Chemical Abstract No. CA99(3):16367e.
Baldi et al., "Effect of a New Antispasmodic Drug, Otilonium Bromide, on the Motor Activity of the Human Gastric Antrum", Clin. Ter. (Roms), 94(2), pp. 159-163, Chemical Abstract No. CA94(5):25196X.
Scarpignato et al., "Effects of Otilonium Bromide on the Gastrointestinal Tract in Vivo", Farmaco, Ed. Prat., 35(5), pp. 249-257, Chemical Abstract No. CA93(5):37410e.
Zappia et al., "Spasmolytic Effect of Otilonium Bromide on Gastrointestinal Motility", Farmaco, Ed. Prat., 35(5), pp. 258-264, Chemical Abstract No. CA93(5):36995n.

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