Use of 6-halo-4-quinolone compounds and pharmaceutical compositi

Details Use of 6-halo-4-quinolone compounds and pharmaceutical compositi Use of 6-halo-4-quinolone compounds and pharmaceutical compositi

1989-08-11

1990-12-18

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142302, 514254, A61K 31495

Patent

active

049786610

ABSTRACT:
The present invention relates to the use of 6-halo-4-quinolone derivatives and pharmaceutical compositions comprising them as active ingredient, for the preparation of a medicament for the therapeutical application in rheumatoid arthritis.
Quinolone derivatives can be intra-articularly administered and act on different points of the pathological process of rheumathoid arthritis without local and general toxicity.

REFERENCES:
patent: 4772605 (1988-09-01), Naik et al.
Bayer et al., The Journal of Infectious Diseases, vol. 152, No. 4 (Oct. 1985), pp. 811-816.
Prere, et al., Chemical Abstracts, 105:75803j (1986).
The Merck Index, 11th ed., 1989, Merck and Co., Inc., Rahway, N.J. pp. 360, 1118.

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