Myoglobin with peroxidase activity

Details Myoglobin with peroxidase activity Myoglobin with peroxidase activity

1996-09-16

1998-12-29

Grimes, Eric

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

530385, C07K 14805, C12N 908

Patent

active

058540415

ABSTRACT:
Myoglobin is shown to have Manganese (Mn.sup.2') binding and peroxidase capacity. Mn binding and peroxidase activity is enhanced by modification of the amino acid sequence of myoglobin to provide a Mn binding site on the surface of the protein near the heme group. Peroxidase activity of myoglobin not specific to Mn is enhanced by substituting amino acids at residues 39, 45, 46, 97 and 107 of myolglobin.

REFERENCES:
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