Process for preparing 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548508, C07D491052, C07D20912

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active

045858772

ABSTRACT:
A process for preparing 1,8-diethyl-1,3,4,9-tetrahydro[3,4-b]-indole-1-acetic acid (etodolac) is disclosed. Etodolac is a useful antiinflammatory and analgesic agent.

REFERENCES:
patent: 3939178 (1976-02-01), Demerson et al.
patent: 4012417 (1977-03-01), Demerson et al.
patent: 4021451 (1977-05-01), Dobson et al.
Demerson et al., J. Med. Chem., 19, 391 (1976).
I. I. Grandberg and T. P. Moskvina, Khim. Geterotsikl. Soedin., 1366 (1972), English translation.

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