Gastric cytoprotection with 3,3'-thiobis[propanoic acid] in oral

Details Gastric cytoprotection with 3,3'-thiobis[propanoic acid] in oral Gastric cytoprotection with 3,3'-thiobis[propanoic acid] in oral

1985-04-22

1986-04-29

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

A61K 3161

Patent

active

045857644

ABSTRACT:
The method of providing cytoprotection of the gastric mucosa in a mammal receiving aspirin (ASA) perorally which comprises orally administering either prior to or in combination with ASA a cytoprotectively effective amount of 3,3'-thiobis[propanoic acid] (TBPA) or in combination with a pharmaceutically acceptable carrier. Also shown is a composition for providing cytoprotection of the gastric mucosa in a mammal receiving ASA perorally which comprises ASA in combination with a cytoprotectively effective amount of TBPA.

REFERENCES:
patent: 2579679 (1951-12-01), Leffler
patent: 3988466 (1977-10-01), Takagi et al.
patent: 4016268 (1977-04-01), Goldenberg et al.
patent: 4491574 (1985-01-01), Seifter et al.
3,3'-Thiobis[propanoic acid], The Merck Index, Tenth Edition, 1983, item 9172, p. 1336.

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